rs12359135

GWAS Catalog Trait Associations (52)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

total lipids in small VLDL

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 8.0e-17
N 136,016
Large GWAS
multi-ancestry

blood VLDL cholesterol amount

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 1.0e-16
N 136,016
Large GWAS
multi-ancestry

total cholesterol measurement, blood VLDL cholesterol amount

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 1.0e-16
N 136,016
Large GWAS
multi-ancestry

phospholipids in VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 2.0e-16
N 136,016
Large GWAS
multi-ancestry

triglycerides in very small VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 4.0e-16
N 136,016
Large GWAS
multi-ancestry

free cholesterol in small VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 5.0e-16
N 136,016
Large GWAS
multi-ancestry

total cholesterol in small VLDL

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 1.0e-15
N 136,016
Large GWAS
multi-ancestry

low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 2.0e-15
N 136,016
Large GWAS
multi-ancestry

apolipoprotein A 1 measurement, apolipoprotein B measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 4.0e-15
N 136,016
Large GWAS
multi-ancestry

triglyceride measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.03
p 6.0e-15
N 136,016
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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