Trait
SNPs associated with total cholesterol measurement, blood VLDL cholesterol amount
270 genetic variants across 71 genes have been associated with total cholesterol measurement, blood VLDL cholesterol amount in published research. Key genes include ABCA6, ABCG8, ABO.
Associated variants270 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs41290120 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs796677417 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs7412 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs2070895 | LIPC | GWAS association (p=8.0e-310) | Large GWAS |
| rs1065853 | — | GWAS association (p=5.0e-251) | Large GWAS |
| rs328 | LPL | GWAS association (p=2.0e-166) | Large GWAS |
| rs821840 | CETP | GWAS association (p=3.0e-147) | Large GWAS |
| rs147985405 | — | GWAS association (p=2.0e-142) | Large GWAS |
| rs429358 | APOE | GWAS association (p=7.0e-138) | Large GWAS |
| rs183130 | CETP | GWAS association (p=2.0e-137) | Large GWAS |
| rs10096633 | — | GWAS association (p=2.0e-131) | Large GWAS |
| rs676210 | APOB | GWAS association (p=3.0e-129) | Large GWAS |
| rs1260326 | GCKR | GWAS association (p=1.0e-114) | Large GWAS |
| rs115849089 | — | GWAS association (p=2.0e-114) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=4.0e-109) | Large GWAS |
| rs10455872 | LPA | GWAS association (p=2.0e-107) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=2.0e-96) | Large GWAS |
| rs2954021 | — | GWAS association (p=2.0e-96) | Large GWAS |
| rs28601761 | — | GWAS association (p=3.0e-96) | Large GWAS |
| rs952275 | — | GWAS association (p=2.0e-87) | Large GWAS |
| rs562338 | — | GWAS association (p=9.0e-87) | Large GWAS |
| rs157595 | — | GWAS association (p=2.0e-82) | Large GWAS |
| rs58542926 | TM6SF2 | GWAS association (p=3.0e-80) | Large GWAS |
| rs584007 | — | GWAS association (p=1.0e-79) | Large GWAS |
| rs115594766 | — | GWAS association (p=1.0e-78) | Large GWAS |
| rs1007205 | — | GWAS association (p=2.0e-74) | Large GWAS |
| rs79439217 | — | GWAS association (p=4.0e-73) | Large GWAS |
| rs200046586 | — | GWAS association (p=1.0e-64) | Large GWAS |
| rs102274 | TMEM258 | GWAS association (p=2.0e-61) | Large GWAS |
| rs56050415 | — | GWAS association (p=2.0e-61) | Large GWAS |
| rs1167996 | DOCK7 | GWAS association (p=3.0e-56) | Large GWAS |
| rs261334 | LIPC | GWAS association (p=1.0e-51) | Large GWAS |
| rs1800588 | LIPC | GWAS association (p=3.0e-49) | Large GWAS |
| rs13240065 | MLXIPL | GWAS association (p=6.0e-48) | Large GWAS |
| rs12916 | HMGCR | GWAS association (p=7.0e-47) | Large GWAS |
| rs646776 | CELSR2 | GWAS association (p=2.0e-44) | Large GWAS |
| rs4665710 | — | GWAS association (p=8.0e-42) | Large GWAS |
| rs6511720 | LDLR | GWAS association (p=2.0e-38) | Large GWAS |
| rs1057208 | PCIF1 | GWAS association (p=3.0e-38) | Large GWAS |
| rs13240994 | MLXIPL | GWAS association (p=5.0e-34) | Large GWAS |
| rs115478735 | ABO | GWAS association (p=6.0e-32) | Large GWAS |
| rs8107974 | — | GWAS association (p=5.0e-31) | Large GWAS |
| rs4564803 | — | GWAS association (p=3.0e-29) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=1.0e-28) | Large GWAS |
| rs629301 | CELSR2 | GWAS association (p=4.0e-28) | Large GWAS |
| rs6874202 | — | GWAS association (p=6.0e-28) | Large GWAS |
| rs11755689 | — | GWAS association (p=2.0e-27) | Large GWAS |
| rs568533060 | — | GWAS association (p=2.0e-27) | Large GWAS |
| rs6999612 | — | GWAS association (p=1.0e-25) | Large GWAS |
| rs102275 | TMEM258 | GWAS association (p=2.0e-25) | Large GWAS |
| rs174529 | MYRF | GWAS association (p=2.0e-25) | Large GWAS |
| rs113298164 | LIPC | GWAS association (p=4.0e-25) | Large GWAS |
| rs117113213 | — | GWAS association (p=8.0e-25) | Large GWAS |
| rs72848251 | — | GWAS association (p=4.0e-24) | Large GWAS |
| rs139974673 | — | GWAS association (p=7.0e-24) | Large GWAS |
| rs72836561 | — | GWAS association (p=3.0e-23) | Large GWAS |
| rs2393776 | HNF1A | GWAS association (p=1.0e-22) | Large GWAS |
| rs117310449 | — | GWAS association (p=2.0e-22) | Large GWAS |
| rs28718232 | — | GWAS association (p=2.0e-22) | Large GWAS |
| rs150844304 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs112259268 | — | GWAS association (p=2.0e-21) | Large GWAS |
| rs181948526 | — | GWAS association (p=1.0e-20) | Large GWAS |
| rs12208357 | SLC22A1 | GWAS association (p=3.0e-19) | Large GWAS |
| rs331 | LPL | GWAS association (p=5.0e-19) | Large GWAS |
| rs174580 | FADS2 | GWAS association (p=8.0e-19) | Large GWAS |
| rs9686661 | C5orf67 | GWAS association (p=8.0e-19) | Large GWAS |
| rs3745151 | NECTIN2 | GWAS association (p=1.0e-18) | Large GWAS |
| rs570794 | FUT2 | GWAS association (p=1.0e-18) | Large GWAS |
| rs2270925 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs635634 | — | GWAS association (p=7.0e-18) | Large GWAS |
| rs10184004 | — | GWAS association (p=8.0e-18) | Large GWAS |
| rs2074493 | HLA-C | GWAS association (p=1.0e-17) | Large GWAS |
| rs295 | LPL | GWAS association (p=2.0e-17) | Large GWAS |
| rs10282584 | — | GWAS association (p=3.0e-17) | Large GWAS |
| rs472495 | PCSK9 | GWAS association (p=5.0e-17) | Large GWAS |
| rs41279633 | — | GWAS association (p=5.0e-17) | Large GWAS |
| rs77960347 | LIPG | GWAS association (p=6.0e-17) | Large GWAS |
| rs2738445 | LDLR | GWAS association (p=1.0e-16) | Large GWAS |
| rs261332 | LIPC | GWAS association (p=1.0e-16) | Large GWAS |
| rs72999033 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs12359135 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs442177 | AFF1 | GWAS association (p=1.0e-16) | Large GWAS |
| rs2000999 | HPR | GWAS association (p=3.0e-16) | Large GWAS |
| rs3777411 | IGF2R | GWAS association (p=4.0e-16) | Large GWAS |
| rs757501676 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs632057 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs1848922 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs10903343 | FDFT1 | GWAS association (p=1.0e-15) | Large GWAS |
| rs9302635 | — | GWAS association (p=3.0e-15) | Large GWAS |
| rs61194703 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs181349205 | LOC105379311 | GWAS association (p=7.0e-15) | Large GWAS |
| rs146203232 | — | GWAS association (p=8.0e-15) | Large GWAS |
| rs1024137 | — | GWAS association (p=8.0e-15) | Large GWAS |
| rs75591007 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs56325564 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs73013176 | SMARCA4 | GWAS association (p=2.0e-14) | Large GWAS |
| rs7133378 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs12691088 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs998584 | POLR1C | GWAS association (p=4.0e-14) | Large GWAS |
| rs114165349 | — | GWAS association (p=5.0e-14) | Large GWAS |
Showing the top 100 of 270 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.