rs117113213

GWAS Catalog Trait Associations (88)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

low density lipoprotein cholesterol measurement

Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele A
OR 0.05
p 5.0e-41
N 361,194
Large GWAS
European
Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.12
p 1.0e-27
N 136,016
Large GWAS
multi-ancestry

intermediate density lipoprotein measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.14
p 1.0e-33
N 136,016
Large GWAS
multi-ancestry

total lipids in IDL

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.14
p 4.0e-33
N 136,016
Large GWAS
multi-ancestry

total lipids in very small VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.14
p 8.0e-33
N 136,016
Large GWAS
multi-ancestry

remnant cholesterol measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.14
p 1.0e-32
N 136,016
Large GWAS
multi-ancestry

esterified cholesterol measurement, intermediate density lipoprotein measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.14
p 3.0e-32
N 136,016
Large GWAS
multi-ancestry

apolipoprotein B measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.13
p 5.0e-32
N 136,016
Large GWAS
multi-ancestry

total cholesterol in IDL

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.13
p 1.0e-31
N 136,016
Large GWAS
multi-ancestry

free cholesterol in very small VLDL measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele A
OR 0.13
p 3.0e-31
N 136,016
Large GWAS
multi-ancestry

concentration of small VLDL particles

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.07
p 4.0e-31
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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