PCIF1
phosphorylated CTD interacting factor 1
Summary
Enables RNA polymerase II C-terminal domain phosphoserine binding activity; S-adenosyl-L-methionine binding activity; and mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA processing; negative regulation of translation; and positive regulation of translation. Located in intercellular bridge; microtubule cytoskeleton; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants44 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs190540063 | 20:44,561,984 | G/C | upstream gene variant | — |
| rs79629788 | 20:44,562,148 | C/T | upstream gene variant | — |
| rs1057208 | 20:44,563,007 | C/T | regulatory region variant | — |
| rs775884705 | 20:44,567,646 | A/G | — | uncertain significance |
| rs201439678 | 20:44,567,662 | C/G | — | uncertain significance |
| rs763290934 | 20:44,567,669 | G/A | — | uncertain significance |
| rs2083448318 | 20:44,567,697 | C/T | — | uncertain significance |
| rs752490933 | 20:44,567,750 | C/G | — | uncertain significance |
| rs764558584 | 20:44,567,955 | G/A | — | uncertain significance |
| rs777519257 | 20:44,569,171 | A/C | — | uncertain significance |
| rs188509769 | 20:44,569,202 | G/A | missense variant | — |
| rs778640382 | 20:44,569,514 | A/C | — | uncertain significance |
| rs371513868 | 20:44,569,565 | C/A | — | uncertain significance |
| rs574698419 | 20:44,569,733 | A/G | — | uncertain significance |
| rs1176324013 | 20:44,569,789 | T/G | — | uncertain significance |
| rs2515502153 | 20:44,569,798 | A/G | — | uncertain significance |
| rs774233890 | 20:44,569,817 | A/G | — | uncertain significance |
| rs141904891 | 20:44,569,822 | C/T | — | uncertain significance |
| rs6065908 | 20:44,569,930 | C/T | intron variant | — |
| rs543025702 | 20:44,570,425 | T/C | — | — |
| rs6017713 | 20:44,570,763 | T/G | — | — |
| rs868159177 | 20:44,572,315 | C/T | — | uncertain significance |
| rs989746518 | 20:44,572,378 | C/T | — | uncertain significance |
| rs1043486085 | 20:44,573,546 | G/A | — | uncertain significance |
| rs200586895 | 20:44,573,550 | C/T | — | uncertain significance |
| rs2083519628 | 20:44,574,450 | G/A | — | uncertain significance |
| rs775372767 | 20:44,574,476 | A/G | — | uncertain significance |
| rs377028795 | 20:44,574,503 | G/A | — | uncertain significance |
| rs748255307 | 20:44,574,744 | G/A | — | uncertain significance |
| rs1600509898 | 20:44,574,947 | G/A | — | uncertain significance |
| rs1171990644 | 20:44,574,992 | C/T | — | uncertain significance |
| rs755982312 | 20:44,575,795 | C/T | — | uncertain significance |
| rs577092226 | 20:44,575,921 | C/T | — | uncertain significance |
| rs757074440 | 20:44,575,990 | T/C | — | uncertain significance |
| rs757958805 | 20:44,576,002 | G/A | — | uncertain significance |
| rs2515515306 | 20:44,576,076 | A/C | — | uncertain significance |
| rs778597602 | 20:44,576,218 | G/A | — | uncertain significance |
| rs1448782034 | 20:44,576,243 | C/T | — | uncertain significance |
| rs531918762 | 20:44,576,293 | C/T | — | uncertain significance |
| rs149514465 | 20:44,576,297 | G/A | — | uncertain significance |
| rs760175614 | 20:44,576,330 | C/T | — | uncertain significance |
| rs374981227 | 20:44,576,344 | C/T | — | uncertain significance |
| rs1203122918 | 20:44,576,361 | G/C | — | uncertain significance |
| rs7679 | 20:44,576,502 | T/C | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.