rs190540063

This is a upstream gene variant variant in the PCIF1 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of phospholipid transfer protein in blood

Allele C
OR 0.38
p 8.0e-32
N 47,745
Large GWAS
European

About PCIF1

Enables RNA polymerase II C-terminal domain phosphoserine binding activity; S-adenosyl-L-methionine binding activity; and mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA processing; negative regulation of translation; and positive regulation of translation. Located in intercellular bridge; microtubule cytoskeleton; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all PCIF1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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