rs1243180

This variant is located in the MLLT10 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

malignant epithelial tumor of ovary

Kuchenbaecker KB et al. “Identification of six new susceptibility loci for invasive epithelial ovarian cancer.” Nature Genetics 47(2):164-71 (2015)

Allele A

OR 1.10

p 1.0e-9

N 13,491

Large GWAS

European

ovarian carcinoma

Pharoah PD et al. “GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.” Nature Genetics 45(4):362-70, 370e1-2 (2013)

Allele T

OR 1.10

p 2.0e-8

N 8,165

Meta-analysis

multi-ancestry

About MLLT10

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

View all MLLT10 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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