MLLT10

MLLT10 histone lysine methyltransferase DOT1L cofactor

Summary

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Known Variants69 total

rsidPosition (GRCh37)AllelesClassClinVar
rs8000825210:21,821,574A/Tupstream gene variant—
rs14366315610:21,823,619C/T—uncertain significance
rs19951507110:21,823,672C/T—likely benign
rs180266910:21,827,796G/A—benign
rs1277986510:21,829,162T/Cintron variant—
rs1101273210:21,830,104A/Gintron variant—
rs19325328010:21,845,795A/T—benign
rs789456510:21,872,913T/G——
rs249175915710:21,875,254C/G—uncertain significance
rs3558737110:21,878,144T/Aintron variant—
rs14423967310:21,884,261T/C—likely benign
rs249193335910:21,901,326G/C—uncertain significance
rs36873897410:21,903,760C/T—likely benign
rs124318010:21,915,619T/G——
rs709070810:21,929,179A/Gintron variant—
rs37089715110:21,940,607T/C—likely benign
rs52982684710:21,959,407A/G—uncertain significance
rs76015732810:21,959,474T/C—uncertain significance
rs78016050610:21,959,531G/A—uncertain significance
rs129058671910:21,962,321G/T—uncertain significance
rs14826855010:21,962,324G/A—uncertain significance
rs14137554110:21,962,367A/G—likely benign
rs20132605210:21,962,427T/C—likely benign
rs15080341310:21,962,453G/C—uncertain significance
rs36928021910:21,962,455G/A—uncertain significance
rs53498497710:21,962,545T/G—uncertain significance
rs36906772310:21,962,563C/T—uncertain significance
rs78035379710:21,962,570C/T—uncertain significance
rs77510682410:21,962,653C/A—uncertain significance
rs14872337510:21,962,792T/G—uncertain significance
rs37762213610:21,970,257A/G—likely benign
rs213140547510:21,971,159T/G—uncertain significance
rs249266952710:22,002,707A/G—uncertain significance
rs37190888910:22,002,716A/G—uncertain significance
rs77644900310:22,002,728T/C—uncertain significance
rs3455182610:22,002,732G/A—benign
rs117998605810:22,002,779G/A—uncertain significance
rs146686655410:22,002,869C/G—uncertain significance
rs19993976910:22,002,871A/G—uncertain significance
rs37314234410:22,002,874A/G—uncertain significance
rs20121195610:22,015,191T/A—likely benign
rs20210607210:22,015,240C/T—uncertain significance
rs20016765510:22,016,778A/G—benign
rs20136462710:22,016,781A/G—likely benign
rs77767553210:22,016,833C/T—uncertain significance
rs74877802610:22,019,852T/C—uncertain significance
rs14255486010:22,019,855G/Amissense variantlikely benign
rs76295019210:22,019,899G/T—uncertain significance
rs133435048010:22,021,917C/T—uncertain significance
rs14407270010:22,021,962A/G—uncertain significance
rs130377387210:22,022,444G/A—uncertain significance
rs74857771410:22,022,492C/T—uncertain significance
rs75867989310:22,022,493C/T—uncertain significance
rs75321446710:22,022,716A/G—uncertain significance
rs249281089710:22,022,749C/T—uncertain significance
rs36886909710:22,022,788G/T—uncertain significance
rs249281178710:22,022,857C/G—uncertain significance
rs76211186010:22,022,889G/A—uncertain significance
rs14753518310:22,022,963G/C—uncertain significance
rs14253924410:22,024,152A/G—likely benign
rs77298517610:22,028,964A/T—uncertain significance
rs53294542810:22,028,976T/G—likely benign
rs75918415010:22,028,979G/C—uncertain significance
rs76010590710:22,029,046G/A—uncertain significance
rs75315336810:22,029,118A/T—uncertain significance
rs135076429810:22,029,160G/A—uncertain significance
rs78112511510:22,030,871C/T—uncertain significance
rs75631297510:22,030,895G/T—uncertain significance
rs707277610:22,032,942A/T——

Gene information from NCBI Gene. Variant classifications from ClinVar.