rs12432645
This variant is located in the DCAF5 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
serum alanine aminotransferase amount
Ghouse J et al. “Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.” Nature Genetics 56(5):827-837 (2024)
Allele T
OR 0.00
p 9.0e-13
N 1,010,710
Large GWAS
European
Headache, type 2 diabetes mellitus
Islam MR et al. “Genetic Overlap Analysis Identifies a Shared Etiology between Migraine and Headache with Type 2 Diabetes.” Genes 13(10) (2022)
Allele T
OR 1.03
p 8.0e-10
N 1,258,523
Large GWAS
European
About DCAF5
Predicted to be involved in negative regulation of fatty acid biosynthetic process. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
View all DCAF5 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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