rs12450895
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
restless legs syndrome
Schormair B et al. “Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.” Nature Genetics 56(6):1090-1099 (2024)
Allele A
OR 0.07
p 4.0e-40
N 1,663,113
Large GWAS
European
Didriksen M et al. “Large genome-wide association study identifies three novel risk variants for restless legs syndrome.” Communications Biology 3(1):703 (2020)
Allele A
OR 1.09
p 1.0e-12
N 480,982
Large GWAS
European
Schormair B et al. “Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.” The Lancet. Neurology 16(11):898-907 (2017)
Allele A
OR 1.08
p 4.0e-14
N 110,851
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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