rs12621459

GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

apolipoprotein B to apolipoprotein A1 ratio

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 1.0e-11
N 450,015
Large GWAS
multi-ancestry

cholesteryl esters in small VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 3.0e-11
N 450,015
Large GWAS
multi-ancestry

concentration of very small VLDL particles

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 3.0e-11
N 450,015
Large GWAS
multi-ancestry

free cholesterol in very small VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 4.0e-11
N 450,015
Large GWAS
multi-ancestry

cholesterol in very small VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 7.0e-11
N 450,015
Large GWAS
multi-ancestry

phospholipids in very small VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 7.0e-11
N 450,015
Large GWAS
multi-ancestry

cholesterol in small VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 8.0e-11
N 450,015
Large GWAS
multi-ancestry

cholesterol in medium VLDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 9.0e-11
N 450,015
Large GWAS
multi-ancestry

intermediate density lipoprotein measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 1.0e-10
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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