rs1275982

GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Agents acting on the renin-angiotensin system use measurement

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.06
p 5.0e-34
N 416,256
Large GWAS
multi-ancestry

systolic blood pressure

Allele T
OR 0.85
p 2.0e-28
N 130,777
Large GWAS
multi-ancestry

mean arterial pressure

Allele T
OR 0.58
p 2.0e-27
N 130,777
Large GWAS
multi-ancestry

diastolic blood pressure

Allele T
OR 0.44
p 5.0e-20
N 130,777
Large GWAS
multi-ancestry

cerebrovascular disorder

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.04
p 4.0e-11
N 597,128
Major Consortium StudyLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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