rs1275984

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

systolic blood pressure

Shi G et al. “Genome-wide variance quantitative trait locus analysis suggests small interaction effects in blood pressure traits.” Scientific Reports 12(1):12649 (2022)
Allele C
OR 0.61
p 1.0e-46
N 396,077
Large GWAS
European
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.02
p 4.0e-24
N 394,642
Large GWAS
European
Hoffmann TJ et al. “Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.” Nature Genetics 49(1):54-64 (2017)
Allele C
OR 0.54
p 7.0e-22
N 99,785
Large GWAS
multi-ancestry

diastolic blood pressure

Shi G et al. “Genome-wide variance quantitative trait locus analysis suggests small interaction effects in blood pressure traits.” Scientific Reports 12(1):12649 (2022)
Allele C
OR 0.32
p 1.0e-40
N 396,079
Large GWAS
European
Hoffmann TJ et al. “Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.” Nature Genetics 49(1):54-64 (2017)
Allele C
OR 0.35
p 2.0e-22
N 99,785
Large GWAS
multi-ancestry

pulse pressure measurement

Hoffmann TJ et al. “Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.” Nature Genetics 49(1):54-64 (2017)
Allele A
OR 0.21
p 2.0e-15
N 321,262
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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