rs12829378
This is a regulatory region variant variant in the ZNF664-RFLNA gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
high density lipoprotein cholesterol measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.04
p 7.0e-28
N 325,634
Major Consortium StudyLarge GWAS
multi-ancestry
triglyceride measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.03
p 1.0e-20
N 355,577
Major Consortium StudyLarge GWAS
multi-ancestry
apolipoprotein A 1 measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.04
p 2.0e-19
N 323,833
Major Consortium StudyLarge GWAS
multi-ancestry
About ZNF664-RFLNA
This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein 664 (Gene ID: 144348) and refilin A (Gene ID: 144347) genes on chromosome 12. The read-through transcript produces a protein that shares sequence identity with the downstream refilin A gene product. [provided by RefSeq, Dec 2016]
View all ZNF664-RFLNA variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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