rs13111599

This is a intron variant variant in the LIN54 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

high density lipoprotein cholesterol measurement

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele A

OR 0.01

p 3.0e-11

N 928,679

Large GWAS

multi-ancestry

Richardson TG et al. “Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.” Plos Medicine 17(3):e1003062 (2020)

Allele A

OR 0.01

p 3.0e-9

N 403,943

Large GWAS

European

apolipoprotein A 1 measurement

Allele A

OR 0.01

p 4.0e-8

N 393,193

Large GWAS

European

About LIN54

LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes (Schmit et al., 2009 [PubMed 19725879]).[supplied by OMIM, Dec 2010]

View all LIN54 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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