rs1318862

This variant is located in the FAT3 gene.

▶

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain volume, caudate nucleus volume

Hibar DP et al. “Common genetic variants influence human subcortical brain structures.” Nature 520(7546):224-9 (2015)

Allele T

OR 26.86

p 6.0e-9

N 13,171

Large GWAS

multi-ancestry

About FAT3

Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within generation of neurons; negative regulation of dendrite development; and retina layer formation. Predicted to be located in dendrite and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

View all FAT3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…