rs13216201

This is a intron variant variant in the TREML2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Lewy body dementia

Guo P et al. “Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer's disease and Parkinson's disease: a large-scale multi-trait association analysis.” Bmc Medicine 20(1):214 (2022)

Allele T

OR 6.12

p 9.0e-10

N 6,618

Large GWAS

European

About TREML2

TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008]

View all TREML2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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