rs13249843

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

neuroticism measurement

Hill WD et al. “Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.” Molecular Psychiatry 25(11):3034-3052 (2020)

Allele G

OR 0.01

p 2.0e-12

N 270,059

Large GWAS

European

left ventricular ejection fraction measurement

Forrest IS et al. “Genetic and phenotypic profiling of supranormal ejection fraction reveals decreased survival and underdiagnosed heart failure.” European Journal of Heart Failure 24(11):2118-2127 (2022)

Allele T

OR 0.14

p 3.0e-9

N 30,557

Large GWAS

African unspecified, Hispanic or Latin American, European, Asian unspecified, NR

diastolic blood pressure, alcohol drinking

Feitosa MF et al. “Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.” Plos One 13(6):e0198166 (2018)

Allele T

OR —

p 2.0e-13

N 133,351

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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