rs13394619

This is a downstream gene variant variant in the GREB1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

endometriosis

Nyholt DR et al. “Genome-wide association meta-analysis identifies new endometriosis risk loci.” Nature Genetics 44(12):1355-9 (2012)

Allele G

OR 1.15

p 6.0e-9

N 13,997

Meta-analysisLarge GWAS

multi-ancestry

About GREB1

This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

View all GREB1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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