GREB1

growth regulating estrogen receptor binding 1

Summary

This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Known Variants149 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs12479436	2:11,666,339	T/G	intergenic variant	—
rs11686574	2:11,684,007	C/T	—	—
rs779592613	2:11,696,756	G/T	—	uncertain significance
rs753609484	2:11,696,778	G/A	—	uncertain significance
rs532741308	2:11,696,820	G/A	—	uncertain significance
rs749067376	2:11,702,652	G/A	—	uncertain significance
rs76904731	2:11,704,284	G/A	upstream gene variant	—
rs6740248	2:11,706,892	C/G	regulatory region variant	—
rs762408918	2:11,716,518	T/A	—	uncertain significance
rs74441544	2:11,718,415	C/A	—	benign
rs752977615	2:11,718,489	C/T	—	uncertain significance
rs368581106	2:11,718,506	G/A	—	uncertain significance
rs139938018	2:11,718,554	G/A	—	uncertain significance
rs141887933	2:11,720,116	G/T	upstream gene variant	—
rs780581197	2:11,720,871	C/T	—	uncertain significance
rs76718398	2:11,720,886	G/A	—	benign
rs16857665	2:11,720,900	G/A	—	benign
rs765549350	2:11,720,947	C/G	—	uncertain significance
rs11674184	2:11,721,535	T/G	upstream gene variant	—
rs10929759	2:11,722,012	C/G	upstream gene variant	—
rs12470971	2:11,725,241	G/A	downstream gene variant	—
rs144245281	2:11,725,294	G/A	—	likely benign
rs776087177	2:11,725,303	C/T	—	likely benign
rs548480650	2:11,725,329	G/A	—	uncertain significance
rs777815509	2:11,725,331	T/C	—	uncertain significance
rs192688544	2:11,725,893	G/T	—	uncertain significance
rs149950879	2:11,725,912	C/T	—	uncertain significance
rs2545546352	2:11,725,929	G/A	—	uncertain significance
rs13394619	2:11,727,507	G/A	downstream gene variant	—
rs4669754	2:11,728,089	C/T	downstream gene variant	—
rs750936323	2:11,728,928	C/G	—	uncertain significance
rs758973590	2:11,728,929	T/G	—	uncertain significance
rs151098036	2:11,728,938	C/T	—	uncertain significance
rs2545575002	2:11,728,961	G/A	—	likely benign
rs765583940	2:11,728,985	G/A	—	uncertain significance
rs760195039	2:11,732,950	G/A	—	uncertain significance
rs753916192	2:11,733,004	C/T	—	uncertain significance
rs746195441	2:11,733,010	C/T	—	uncertain significance
rs374620101	2:11,733,033	G/A	—	uncertain significance
rs937980781	2:11,733,081	G/T	—	uncertain significance
rs759359789	2:11,733,096	G/A	—	uncertain significance
rs759873232	2:11,733,234	T/C	—	uncertain significance
rs200479286	2:11,733,260	C/G	—	likely benign
rs372686737	2:11,735,407	G/A	—	uncertain significance
rs373238759	2:11,735,444	T/A	—	uncertain significance
rs777505379	2:11,736,243	A/T	—	uncertain significance
rs1229627625	2:11,736,299	T/C	—	uncertain significance
rs756165681	2:11,738,003	A/G	—	uncertain significance
rs201308001	2:11,738,023	T/C	—	uncertain significance
rs772953684	2:11,738,092	G/A	—	uncertain significance
rs751991512	2:11,738,813	G/T	—	uncertain significance
rs201947141	2:11,738,846	G/A	—	likely benign
rs771844304	2:11,738,865	T/C	—	uncertain significance
rs530928171	2:11,738,884	C/T	—	uncertain significance
rs370221339	2:11,738,920	A/G	—	uncertain significance
rs772620258	2:11,738,960	T/A	—	uncertain significance
rs772234057	2:11,741,048	C/T	—	uncertain significance
rs745397363	2:11,742,575	C/T	—	uncertain significance
rs2545660965	2:11,742,626	A/T	—	uncertain significance
rs371609460	2:11,750,834	C/T	—	uncertain significance
rs201474551	2:11,750,870	C/T	—	uncertain significance
rs375384889	2:11,750,900	C/T	—	uncertain significance
rs182841070	2:11,750,979	C/T	—	benign
rs370772266	2:11,750,980	G/A	—	uncertain significance
rs889402087	2:11,751,017	C/T	—	uncertain significance
rs2545719110	2:11,752,621	A/G	—	uncertain significance
rs764044844	2:11,755,263	G/T	—	uncertain significance
rs201040158	2:11,755,347	G/A	—	uncertain significance
rs368967242	2:11,756,766	C/T	—	likely benign
rs542798799	2:11,756,787	A/G	—	uncertain significance
rs200585700	2:11,756,802	G/A	—	likely benign
rs759041147	2:11,758,428	G/A	—	uncertain significance
rs73175262	2:11,758,431	G/A	missense variant	—
rs201632670	2:11,758,436	C/T	—	likely benign
rs199936103	2:11,758,467	G/C	—	uncertain significance
rs372658298	2:11,758,468	A/G	—	uncertain significance
rs114783798	2:11,758,491	C/T	—	benign
rs760328963	2:11,758,499	C/T	—	likely benign
rs371773393	2:11,758,500	G/A	—	likely benign
rs367781781	2:11,758,503	G/C	—	uncertain significance
rs777852827	2:11,758,522	G/C	—	uncertain significance
rs775859147	2:11,758,591	C/T	—	uncertain significance
rs768033894	2:11,758,594	C/T	—	uncertain significance
rs368897613	2:11,758,602	G/A	—	uncertain significance
rs372644788	2:11,758,620	G/T	—	uncertain significance
rs372908920	2:11,758,647	A/G	—	uncertain significance
rs1316820539	2:11,758,675	C/T	—	uncertain significance
rs1402515469	2:11,758,690	C/T	—	uncertain significance
rs61741337	2:11,758,703	G/A	—	benign
rs202215699	2:11,758,707	G/A	—	likely benign
rs200183889	2:11,758,717	C/T	—	uncertain significance
rs766641086	2:11,758,739	G/C	—	uncertain significance
rs756800770	2:11,758,762	G/A	—	uncertain significance
rs201134103	2:11,758,904	G/C	—	uncertain significance
rs778984881	2:11,758,939	G/A	—	uncertain significance
rs762337800	2:11,758,956	C/T	—	uncertain significance
rs570071394	2:11,758,957	G/A	—	uncertain significance
rs199868861	2:11,758,959	C/T	—	uncertain significance
rs751193642	2:11,758,977	G/A	—	uncertain significance
rs574305648	2:11,758,983	C/T	—	uncertain significance

Showing 100 of 149 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.