rs13409360

This is a downstream gene variant variant.

▶

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

serum alanine aminotransferase amount

Vujkovic M et al. “A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.” Nature Genetics 54(6):761-771 (2022)

Allele A

OR 0.05

p 2.0e-15

N 164,197

Large GWAS

European

triglyceride measurement, C-reactive protein measurement

Ligthart S et al. “Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.” Bmc Genomics 17:443 (2016)

Allele A

OR —

p 5.0e-15

N 161,598

Large GWAS

triglyceride measurement

Graham SE et al. “The power of genetic diversity in genome-wide association studies of lipids.” Nature 600(7890):675-679 (2021)

Allele A

OR 0.01

p 4.0e-9

N 1,320,016

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…