rs1361754

This variant is located in the PM20D1 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

QT interval

Bihlmeyer NA et al. ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. Circulation. Genomic and Precision Medicine 11(1):e001758 (2018)
Allele G
OR 0.47
p 1.0e-9
N 95,626
Large GWAS
multi-ancestry

ClinVar annotation

Benign★★★
2 submitters1 publication
View on ClinVar →

About PM20D1

Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including amide biosynthetic process; amide catabolic process; and amino acid metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]

View all PM20D1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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