rs1362931
This is a intron variant variant in the PLA2G7 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
lipoprotein-associated phospholipase A(2) measurement
Chu AY et al. “Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.” Circulation. Cardiovascular Genetics 5(6):676-85 (2012)
Allele A
OR 0.02
p 3.0e-19
N 6,851
Large GWAS
European
About PLA2G7
The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009]
View all PLA2G7 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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