rs1379745083
This variant is located in the MAP3K14 gene.
▶ClinVar annotation
About MAP3K14
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
View all MAP3K14 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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