rs1382879

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

thyroid disease, drug use measurement

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele T

OR 0.09

p 7.0e-23

N 400,487

Major Consortium StudyLarge GWAS

multi-ancestry

Thyroid stimulating hormone level

Malinowski JR et al. “Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.” Plos One 9(12):e111301 (2014)

Allele G

OR 0.09

p 7.0e-18

N 4,852

Large GWAS

multi-ancestry

hypothyroidism

Teumer A et al. “Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.” Nature Communications 9(1):4455 (2018)

Allele T

OR 0.15

p 2.0e-9

N 53,323

Large GWAS

European

thyroid disease

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele T

OR 0.08

p 1.0e-19

N 404,034

Major Consortium StudyLarge GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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