rs138447525
This is a intron variant variant in the SH3YL1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
low molecular weight phosphotyrosine protein phosphatase measurement
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele T
OR 1.21
p 2.0e-22
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
About SH3YL1
Enables phosphatase binding activity and phosphatidylinositol binding activity. Predicted to be involved in regulation of ruffle assembly. Predicted to act upstream of or within phosphatidylinositol biosynthetic process. Located in ruffle membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all SH3YL1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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