rs139077859
This is a downstream gene variant variant in the LRRC37A gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
preserved ratio impaired spirometry
Higbee DH et al. “Genome-wide association study of preserved ratio impaired spirometry (PRISm).” The European Respiratory Journal 63(1) (2024)
Allele G
OR 0.99
p 3.0e-16
N 289,782
Large GWAS
European
white matter integrity
Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele A
OR 0.09
p 5.0e-14
N 20,860
Major Consortium StudyLarge GWAS
European
maximal oxygen uptake measurement
Hanscombe KB et al. “The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.” Genome Medicine 13(1):180 (2021)
Allele G
OR 0.03
p 2.0e-8
N 70,783
Large GWAS
European
About LRRC37A
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all LRRC37A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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