rs139123090
This variant is located in the C10orf90 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
age-related hearing impairment
Ivarsdottir EV et al. “The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis.” Communications Biology 4(1):706 (2021)
Allele A
OR 17.32
p 4.0e-10
N 713,633
Large GWAS
European
▶ClinVar annotation
Benign★☆☆☆
1 submitter1 publicationAbout C10orf90
Predicted to enable histone deacetylase binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including protein stabilization; regulation of cell cycle process; and response to ionizing radiation. Located in cytoskeleton; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all C10orf90 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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