Trait
SNPs associated with Age-Related Hearing Impairment
86 genetic variants across 32 genes have been associated with Age-Related Hearing Impairment in published research. Key genes include ACADVL, AGBL2, ARHGEF28.
Associated variants86 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs36062310 | — | GWAS association (p=4.0e-32) | Meta-analysis |
| rs10901863 | — | GWAS association (p=2.0e-26) | Meta-analysis |
| rs4413512 | — | GWAS association (p=1.0e-25) | Meta-analysis |
| rs2877561 | ILDR1 | GWAS association (p=3.0e-25) | Meta-analysis |
| rs1981809 | — | GWAS association (p=1.0e-20) | Meta-analysis |
| rs4714678 | — | GWAS association (p=7.0e-20) | Meta-analysis |
| rs72963168 | — | GWAS association (p=4.0e-19) | Meta-analysis |
| rs5756795 | TRIOBP | GWAS association (p=1.0e-17) | Meta-analysis |
| rs9493627 | EYA4 | GWAS association (p=1.0e-17) | Meta-analysis |
| rs67307131 | — | GWAS association (p=5.0e-15) | Meta-analysis |
| rs1566128 | — | GWAS association (p=1.0e-14) | Meta-analysis |
| rs132931 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs7939493 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs6545432 | — | GWAS association (p=2.0e-13) | Meta-analysis |
| rs72622585 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs323693 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs13148153 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs115596275 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs4660885 | — | GWAS association (p=4.0e-12) | Meta-analysis |
| rs143282422 | CDH23 | GWAS association (p=6.0e-12) | Meta-analysis |
| rs7313797 | — | GWAS association (p=7.0e-12) | Meta-analysis |
| rs11238325 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs13171669 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs4132250 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs920701 | — | GWAS association (p=5.0e-11) | Meta-analysis |
| rs7525101 | — | GWAS association (p=9.0e-11) | Meta-analysis |
| rs7764856 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs143796236 | FSCN2 | GWAS association (p=3.0e-10) | Meta-analysis |
| rs2393729 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs741475 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs2296508 | — | GWAS association (p=4.0e-10) | Meta-analysis |
| rs222835 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs4732339 | TMEM213 | GWAS association (p=6.0e-10) | Meta-analysis |
| rs11152089 | CCDC68 | GWAS association (p=9.0e-10) | Meta-analysis |
| rs11643684 | MMP2-AS1 | GWAS association (p=2.0e-09) | Meta-analysis |
| rs11881070 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs3915060 | ILDR1 | GWAS association (p=4.0e-09) | Meta-analysis |
| rs13268718 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs61734651 | COL9A3 | GWAS association (p=8.0e-09) | Meta-analysis |
| rs147893329 | — | GWAS association (p=8.0e-09) | Meta-analysis |
| rs6500458 | SPIRE2 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs1097215 | EXOC6 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs61784824 | IPP | GWAS association (p=2.0e-08) | Meta-analysis |
| rs2332035 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs566673 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs150903480 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs35887622 | GJB2 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs141403654 | AGBL2 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs10403118 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs9517282 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs13337678 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs12112406 | — | GWAS association (p=5.0e-08) | Meta-analysis |
| rs62033400 | FTO | GWAS association (p=5.0e-08) | Meta-analysis |
| rs58389158 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs6453022 | ARHGEF28 | GWAS association (p=3.0e-23) | Large GWAS |
| rs118174674 | LOXHD1 | GWAS association (p=2.0e-22) | Large GWAS |
| rs1126809 | TYR | GWAS association (p=2.0e-21) | Large GWAS |
| rs137960856 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs2242416 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs1566129 | NID2 | GWAS association (p=4.0e-15) | Large GWAS |
| rs201291779 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs146694394 | SYNJ2 | GWAS association (p=8.0e-14) | Large GWAS |
| rs141952919 | SLC26A5 | GWAS association (p=2.0e-13) | Large GWAS |
| rs132924 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs4932196 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs72622588 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs761934676 | TBC1D24 | GWAS association (p=6.0e-13) | Large GWAS |
| rs12441297 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs55635402 | TUB | GWAS association (p=4.0e-12) | Large GWAS |
| rs2703636 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs1344011 | CCDC68 | GWAS association (p=3.0e-11) | Large GWAS |
| rs9394952 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs13147559 | CLRN2 | GWAS association (p=4.0e-11) | Large GWAS |
| rs12784122 | LINC02655 | GWAS association (p=8.0e-11) | Large GWAS |
| rs2354376 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs749405486 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs139123090 | C10orf90 | GWAS association (p=4.0e-10) | Large GWAS |
| rs10531957 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs3014246 | CCDC17 | GWAS association (p=1.0e-09) | Large GWAS |
| rs11996715 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs557563970 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs17671352 | ACADVL | GWAS association (p=9.0e-09) | Large GWAS |
| rs74543584 | MPZL2 | GWAS association (p=1.0e-08) | Large GWAS |
| rs7752421 | SNAP91 | GWAS association (p=1.0e-08) | Large GWAS |
| rs765488721 | TBX2 | GWAS association (p=4.0e-08) | Large GWAS |
| rs764272881 | SLC4A11 | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.