rs4714678
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
age-related hearing impairment
Trpchevska N et al. “Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss.” American Journal of Human Genetics 109(6):1077-1091 (2022)
Allele A
OR 0.01
p 7.0e-20
N 723,266
Meta-analysisLarge GWAS
European
systolic blood pressure
Takeuchi F et al. “Interethnic analyses of blood pressure loci in populations of East Asian and European descent.” Nature Communications 9(1):5052 (2018)
Allele A
OR 0.57
p 1.0e-17
N 130,777
Large GWAS
multi-ancestry
mean arterial pressure
Takeuchi F et al. “Interethnic analyses of blood pressure loci in populations of East Asian and European descent.” Nature Communications 9(1):5052 (2018)
Allele A
OR 0.38
p 9.0e-16
N 130,777
Large GWAS
multi-ancestry
blood urea nitrogen amount
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.01
p 8.0e-11
N 492,819
Large GWAS
multi-ancestry
serum urea amount
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.02
p 3.0e-10
N 355,637
Major Consortium StudyLarge GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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