rs139813823
This variant is located in the CXCL10 gene.
▶ClinVar annotation
Benign★★★☆
2 submitters2 publicationsAbout CXCL10
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020]
View all CXCL10 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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