rs141353897

This variant is located in the IL22 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About IL22

This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. The encoded protein is a crucial cytokine that regulates host immunity in infectious diseases, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Dec 2021]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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