rs141754817

This variant is located in the ALPI gene.

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ClinVar annotation

Likely Benign★☆☆☆

2 submitters1 publication

ALPI-related disorder; not provided

About ALPI

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014]

View all ALPI variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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