rs142548315

This variant is located in the GRK4 gene.

ClinVar annotation

Uncertain Significance☆☆☆
1 submitter

not specified

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About GRK4

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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