rs146088439
This is a intron variant variant in the IPO9 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
late-onset Alzheimers disease
Ge YJ et al. “Genome-wide meta-analysis identifies ancestry-specific loci for Alzheimer's disease.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 20(9):6243-6256 (2024)
Allele A
OR 0.64
p 3.0e-10
N 1,392
Meta-analysis
East Asian
About IPO9
Enables histone binding activity; histone chaperone activity; and nuclear import signal receptor activity. Involved in proteasome localization and protein import into nucleus. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
View all IPO9 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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