Trait
SNPs associated with late-onset Alzheimers disease
20 genetic variants across 7 genes have been associated with late-onset Alzheimers disease in published research. Key genes include ABI3, APOE, ATP5F1C.
Associated variants20 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7412 | APOE | GWAS association (p=2.0e-21) | Meta-analysis |
| rs114812713 | — | GWAS association (p=2.0e-13) | Meta-analysis |
| rs7920721 | LOC105376412 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs6140401 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs10806784 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs372437773 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs146088439 | IPO9 | GWAS association (p=3.0e-10) | Meta-analysis |
| rs79872316 | LOC101927967 | GWAS association (p=3.0e-10) | Meta-analysis |
| rs138190086 | — | GWAS association (p=5.0e-09) | Meta-analysis |
| rs593742 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs7185636 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs2830500 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs62039712 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs2632516 | — | GWAS association (p=5.0e-08) | Meta-analysis |
| rs75932628 | TREM2 | GWAS association (p=5.0e-24) | Large GWAS |
| rs143332484 | TREM2 | GWAS association (p=2.0e-14) | Large GWAS |
| rs616338 | ABI3 | GWAS association (p=5.0e-10) | Large GWAS |
| rs139967528 | ATP5F1C | GWAS association (p=6.0e-10) | Large GWAS |
| rs112404845 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs16961023 | — | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.