rs146362319

This is a downstream gene variant variant in the LGI4 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

potassium measurement

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.10
p 7.0e-12
N 603,756
Major Consortium StudyLarge GWAS
multi-ancestry

About LGI4

Involved in regulation of myelination. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Implicated in arthrogryposis multiplex congenita-1 and childhood absence epilepsy. [provided by Alliance of Genome Resources, Jul 2025]

View all LGI4 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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