rs147224410

This is a intron variant variant in the LRP1B gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

lysophosphatidylcholine 15:0 measurement

Cadby G et al. “Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.” Nature Communications 13(1):3124 (2022)

Allele C

OR 0.59

p 3.0e-8

N 4,492

Large GWAS

European

About LRP1B

This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016]

View all LRP1B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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