rs1473219900
This variant is located in the HTRA1 gene.
▶ClinVar annotation
About HTRA1
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]
View all HTRA1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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