rs148777337
This variant is located in the DVL2 gene.
▶ClinVar annotation
Benign★★★☆
2 submitters2 publicationsAbout DVL2
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008]
View all DVL2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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