rs149394327

GWAS Catalog Trait Associations (53)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

platelet crit

Allele C
OR 0.10
p 4.0e-84
N 394,642
Large GWAS
European

amount of platelet-derived growth factor C (human) in blood

Allele C
OR 0.33
p 4.0e-81
N 47,745
Large GWAS
European

platelet count

Allele C
OR 0.10
p 4.0e-79
N 542,827
Large GWAS
European
Allele C
OR 0.08
p 7.0e-60
N 394,642
Large GWAS
European

complement C1r subcomponent-like protein measurement

Allele C
OR 0.30
p 2.0e-72
N 47,745
Large GWAS
European

Dickkopf-related protein 4 measurement

Allele C
OR 0.69
p 3.0e-54
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)

level of angiopoietin-related protein 1 in blood serum

Allele C
OR 0.22
p 2.0e-48
N 47,745
Large GWAS
European

LDL particle size

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.08
p 1.0e-43
N 450,015
Large GWAS
multi-ancestry

hepatocyte growth factor-like protein level

Allele C
OR 0.07
p 4.0e-41
N 47,745
Large GWAS
European

receptor tyrosine-protein kinase erbb-3 measurement

Allele C
OR 0.18
p 1.0e-35
N 47,745
Large GWAS
European

free cholesterol to total lipids in small HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.07
p 2.0e-32
N 450,015
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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