rs149771079
This variant is located in the NYNRIN gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Ischemic stroke
Yamada Y et al. “Identification of nine genes as novel susceptibility loci for early-onset ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage.” Biomedical Reports 9(1):8-20 (2018)
Allele A
OR 3.33
p 5.0e-8
N 6,224
Large GWAS
East Asian
▶ClinVar annotation
Likely Benign★☆☆☆
1 submitter1 publicationAbout NYNRIN
Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be involved in DNA integration; DNA synthesis involved in DNA repair; and DNA-templated DNA replication. Predicted to be located in membrane. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all NYNRIN variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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