rs149940960
This is a 3 prime utr variant variant in the GREB1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
response to combination chemotherapy, serum alanine aminotransferase amount
Liu Y et al. “Genome-Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy.” Clinical Pharmacology and Therapeutics 102(1):131-140 (2017)
Allele T
OR 6.67
p 2.0e-8
N 715
Small GWAS
multi-ancestry
About GREB1
This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
View all GREB1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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