rs150781447
This is a protein-altering variant in the TBC1D30 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
insulin measurement
Huyghe JR et al. “Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.” Nature Genetics 45(2):197-201 (2013)
Allele T
OR 0.20
p 1.0e-16
N 8,229
Large GWAS
European
About TBC1D30
Enables GTPase activator activity and small GTPase binding activity. Involved in negative regulation of cilium assembly and positive regulation of GTPase activity. Located in several cellular components, including ciliary basal body; cytosol; and nuclear body. [provided by Alliance of Genome Resources, Jul 2025]
View all TBC1D30 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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