rs1556784457

This variant is located in the XAGE3 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About XAGE3

This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]

View all XAGE3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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