rs1558861

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GWAS Catalog Trait Associations (27)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

fatty acid amount

Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)
Allele C
OR —
p 1.0e-300
N 239,268
Large GWAS
European

metabolic syndrome

Ho CY et al. “A Genome-Wide Association Study of Metabolic Syndrome in the Taiwanese Population.” Nutrients 16(1) (2023)
Allele T
OR 0.21
p 6.0e-61
N 107,230
Large GWAS
East Asian

triglyceride measurement

Kooner JS et al. “Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.” Nature Genetics 40(2):149-51 (2008)
Allele C
OR 17.00
p 2.0e-26
N 2,011
Large GWAS
multi-ancestry
Harshfield EL et al. “Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.” Bmc Medicine 19(1):232 (2021)
Allele C
OR 0.13
p 6.0e-23
N 5,662
Large GWAS
South Asian

Hypertriglyceridemia

Ram R et al. “A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.” Clinical Genetics 91(3):371-378 (2017)
Allele C
OR 1.74
p 4.0e-24
N 4,086
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)

sterol level

Harshfield EL et al. “Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.” Bmc Medicine 19(1):232 (2021)
Allele C
OR 0.10
p 6.0e-23
N 5,662
Large GWAS
South Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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