rs157935
This variant is located in the LINC-PINT gene.
▶GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
basal cell carcinoma
Stacey SN et al. “New basal cell carcinoma susceptibility loci.” Nature Communications 6:6825 (2015)
Allele T
OR 1.21
p 4.0e-20
N 270,930
Large GWAS
multi-ancestry
Stacey SN et al. “Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.” Human Molecular Genetics 23(11):3045-53 (2014)
Allele T
OR 1.23
p 9.0e-11
N 113,616
Large GWAS
European
skin neoplasm
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.08
p 6.0e-15
N 670,929
Large GWAS
multi-ancestry
non-melanoma skin carcinoma
Visconti A et al. “Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.” Nature Communications 9(1):1684 (2018)
Allele G
OR 1.14
p 9.0e-10
N 187,652
Large GWAS
testosterone measurement
Venkatesh SS et al. “Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum.” Nature Genetics 57(5):1107-1118 (2025)
Allele G
OR 0.02
p 5.0e-8
N 243,951
Large GWAS
European, South Asian
serum albumin amount
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.02
p 3.0e-11
N 372,948
Major Consortium StudyLarge GWAS
European
sex hormone-binding globulin measurement
Ruth KS et al. “Using human genetics to understand the disease impacts of testosterone in men and women.” Nature Medicine 26(2):252-258 (2020)
Allele G
OR 0.01
p 5.0e-27
N 180,094
Large GWAS
European
About LINC-PINT
Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all LINC-PINT variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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