rs1588635

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

hypothyroidism

Figuerêdo J et al. Uncovering the shared genetic components of thyroid disorders and reproductive health. European Journal of Endocrinology 191(2):211-222 (2024)
Allele C
OR 1.24
p 8.0e-153
N 691,986
Large GWAS
European

thyroid carcinoma

Gudmundsson J et al. A genome-wide association study yields five novel thyroid cancer risk loci. Nature Communications 8:14517 (2017)
Allele A
OR 1.69
p 2.0e-58
N 290,551
Large GWAS
European

differentiated thyroid carcinoma

Truong T et al. Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium. International Journal of Cancer 148(12):2935-2946 (2021)
Allele C
OR 0.61
p 2.0e-21
N 3,527
Major Consortium StudyLarge GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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