rs1589916143

This variant is located in the IRF7 gene.

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ClinVar annotation

Uncertain Significance★★★☆

2 submitters2 publications

Immunodeficiency 39; not provided

About IRF7

This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses. [provided by RefSeq, Jul 2021]

View all IRF7 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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