rs1697421
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (8)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
phosphorus measurement
Kestenbaum B et al. “Common genetic variants associate with serum phosphorus concentration.” Journal of the American Society of Nephrology : Jasn 21(7):1223-32 (2010)
Allele A
OR —
β 0.050
p 1.0e-27
N 16,264
Large GWAS
European
cerebrospinal fluid composition attribute, phosphoethanolamine measurement
Wang C et al. “Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits.” Nature Genetics 56(12):2685-2695 (2024)
Allele T
OR 0.03
p 2.0e-23
N 2,311
Large GWAS
European
DSGEGDFXAEGGGVR-to-ADpSGEGDFXAEGGGVR ratio
Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele T
OR —
β 0.056
p 2.0e-20
N 2,019
Large GWAS
European
cerebrospinal fluid composition attribute, glycerol-3-phosphate measurement
Wang C et al. “Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits.” Nature Genetics 56(12):2685-2695 (2024)
Allele T
OR 0.03
p 1.0e-19
N 2,602
Large GWAS
European
choline phosphate measurement
Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele T
OR 0.13
p 3.0e-17
N 8,245
Large GWAS
European
C-reactive protein measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.02
p 2.0e-15
N 394,642
Large GWAS
European
ADSGEGDFXAEGGGVR-to-ADpSGEGDFXAEGGGVR ratio
Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele T
OR —
β 0.042
p 3.0e-14
N 2,029
Large GWAS
European
vitamin B6 measurement
Keene KL et al. “Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial.” Frontiers in Public Health 2:112 (2014)
Allele T
OR 0.17
p 7.0e-10
N 2,100
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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