rs1729951
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
neuroticism measurement
Luciano M et al. “Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.” Nature Genetics 50(1):6-11 (2018)
Allele T
OR 7.39
p 1.0e-13
N 329,821
Large GWAS
European
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele T
OR 6.78
p 1.0e-11
N 380,506
Large GWAS
European
Wendt FR et al. “Sex-Specific Genetic and Transcriptomic Liability to Neuroticism.” Biological Psychiatry 93(3):243-252 (2023)
Allele T
OR 0.07
p 2.0e-9
N 145,669
Large GWAS
European
worry measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele T
OR 6.00
p 2.0e-9
N 372,869
Large GWAS
European
irritable bowel syndrome
Alemany S et al. “Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants.” Journal of Translational Medicine 21(1):272 (2023)
Allele T
OR 0.01
p 9.0e-9
N 887,490
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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